CUET UG 2027 / Biology syllabus

CUET UG 2027 · Paper 304

CUET Biology Syllabus 2027: Units, Chapters and Books

The official CUET UG Biology / Biological Science / Biotechnology / Biochemistry syllabus (paper 304), unit by unit, with the book chapter each unit comes from, links to our class 12 notes for every chapter, what changed from 2025 to 2026, and where to practise.

Practise CUET Biology in the Study OS Official NTA syllabus PDF

2027 status: NTA has not released the CUET UG 2027 syllabus. This page shows the official CUET UG 2026 Biology syllabus, the latest available, and will be updated when NTA publishes the 2027 version.

CUET Biology at a glance

Paper code: 304 (Biology / Biological Science / Biotechnology / Biochemistry)
Questions: 50 multiple-choice questions, all compulsory
Time: 60 minutes
Marking: +5 for a correct answer, minus 1 for a wrong answer; 250 maximum
Syllabus: 5 units, 13 chapters in our chapter map

How the CUET Biology paper is structured

CUET Biology (paper 304) covers the same paper for Biology, Biological Science, Biotechnology and Biochemistry. It is class 12 only, in five units the PDF numbers VI to X because it copies the CBSE class 12 numbering: Reproduction, Genetics and Evolution, Biology and Human Welfare, Biotechnology and its Applications, and Ecology and Environment.

Each unit maps to whole chapters of the rationalised NCERT Biology class 12 book, all 13 of them. Every chapter below links to our class 12 notes for that chapter.

CUET Biology syllabus, unit by unit

Unit titles and topics as printed in NTA’s CUET UG 2026 syllabus PDF.

Unit VI

Reproduction

Sexual Reproduction in Flowering Plants: Pre-fertilisation: structure and events - stamen, microsporangium and pollen grain, pistil, megasporangium and embryo sac; Development of male (microsporogenesis) and female gametophyte (megasporogenesis); Pollination - types, agents and examples; Out breeding devices; Pollen-pistil interaction; Double fertilisation; Post fertilisation: structure and events - development of endosperm and embryo; Formation of seed and fruit and parthenocarpy; Significance of seed in angiosperms; Apomixis and polyembryony.
Human Reproduction: Male and female reproductive system; Microscopic anatomy of testis and ovary; Gametogenesis - spermatogenesis and oogenesis; Menstrual cycle; Fertilisation, embryo development up to blastocyst formation, implantation; Pregnancy and embryonic development and placenta; Parturition and lactation.
Reproductive Health: Problems and strategies - amniocentesis; Population stabilisation and birth control - various methods of contraception; Medical termination of pregnancy (MTP); Sexually transmitted infections (STIs); Infertility - Assisted reproductive technologies (IVF, ZIFT, GIFT, ICSI and IUI).

Unit VII

Genetics and Evolution

Principles of Inheritance and Variation: Mendel's law of inheritance: Inheritance of one gene - Law of dominance, law of segregation (test and back cross); Deviation from Mendelism - incomplete dominance and co-dominance; Multiple alleles and inheritance of blood groups; Inheritance of two genes - law of independent assortment, dihybrid cross; Chromosomal theory of inheritance; Linkage and recombination; Polygenic inheritance; Pleiotropy; Sex determination in humans, birds and honey bee; Mutation; Genetic disorders - pedigree analysis, Mendelian disorders (colour blindness, haemophilia, sickle-cell anaemia, phenylketonuria and thalassemia), chromosomal disorders in humans (aneuploidy, polyploidy, Down's syndrome, Turner's syndrome and Klinefelter's syndrome).
Molecular Basis of Inheritance: Structure and packaging of DNA helix; Search for genetic material (transforming principle and Hershey-Chase experiment); Properties of genetic material; Replication (Meselson and Stahl's experiment); Transcription - transcription unit and gene; RNA world - types of RNA and process of transcription; Genetic code and mutations; tRNA; Translation; Regulation of gene expression - Lac operon; Human Genome Project (goals, salient features and applications); DNA fingerprinting (polymorphism and VNTR).
Evolution: Origin of life - Miller's experiment; Concepts of evolution (Darwin's contribution); Evidences for evolution (embryology, paleontology, comparative anatomy, divergent and convergent evolution and industrial evolution); Adaptive radiation; Biological evolution; Natural selection; Mechanism of evolution; Hardy-Weinberg principle and affecting factors (gene migration, genetic drift, mutation, recombination and natural selection); Evolution of plants and vertebrates through geological periods; Origin and evolution of man.

Unit VIII

Biology and Human Welfare

Human Health and Disease: Introduction about health; Common diseases in humans (typhoid, pneumonia, common cold, malaria, amoebiasis, ascariasis, filariasis and ringworms); Immunity - innate and acquired immunity, active and passive immunity, vaccination and immunisation, allergies, auto-immunity and immune system in human; AIDS; Cancer; Drugs and alcohol abuse - adolescence, addiction, effects of drug abuse, prevention and control.
Microbes in Human Welfare: Microbes in household products; Microbes in industrial products - beverages, antibiotics, enzymes and bioactive molecules; Microbes in sewage treatment and production of biogas, Microbes as biocontrol agents and biofertilisers.

Unit IX

Biotechnology and its Applications

Biotechnology: Principles and Processes: Principles of biotechnology; Tools of recombinant DNA technology - restriction enzymes, cloning vectors, competent host; Processes of rDNA technology - isolation, amplification of gene (PCR), insertion of rDNA in host and bioreactors; Downstream processing.
Biotechnology and its Applications: Application of biotechnology in agriculture - tissue culture, genetically modified organisms, Bt cotton, RNA interference; Biotechnology in medicine - insulin, gene therapy and molecular diagnosis; Transgenic animals; Ethical issues - biopiracy and patents.

Unit X

Ecology and Environment

Organisms and Populations: Population attributes - birth and death rate, age pyramids; Population growth - exponential and logistic growth; Life history variation; Population interactions - predation, competition, parasitism, commensalism, mutualism and amensalism.
Ecosystem: Structure and function; Productivity; Decomposition; Energy flow - different trophic levels, food chain and food web; Ecological pyramids - pyramid of energy, biomass and number.
Biodiversity and Conservation: Biodiversity - concept, patterns and importance; Causes of biodiversity loss; Biodiversity conservation - approaches (narrowly utilitarian, broadly utilitarian and ethical); Methods of biodiversity conservation - in situ (endemism, hotspots and sacred groves etc.), ex situ (Wildlife safaris, zoological parks and cryopreservation etc.).

Chapter map

Each row is one chapter of study, with the book it comes from. Where a syllabus topic is missing from that book, the row says so. Every NCERT chapter links to our class 12 notes for it.

Sexual Reproduction in Flowering PlantsNCERT Biology Class 12, chapter 1Class 12 notes
Human ReproductionNCERT Biology Class 12, chapter 2Class 12 notes
Reproductive HealthNCERT Biology Class 12, chapter 3Class 12 notes
Principles of Inheritance and VariationNCERT Biology Class 12, chapter 4Class 12 notes
Molecular Basis of InheritanceNCERT Biology Class 12, chapter 5Class 12 notes
EvolutionNCERT Biology Class 12, chapter 6Class 12 notes
Human Health and DiseaseNCERT Biology Class 12, chapter 7Class 12 notes
Microbes in Human WelfareNCERT Biology Class 12, chapter 8Class 12 notes
Biotechnology: Principles and ProcessesNCERT Biology Class 12, chapter 9Class 12 notes
Biotechnology and its ApplicationsNCERT Biology Class 12, chapter 10Class 12 notes
Organisms and PopulationsNCERT Biology Class 12, chapter 11Class 12 notes
EcosystemNCERT Biology Class 12, chapter 12Class 12 notes
Biodiversity and ConservationNCERT Biology Class 12, chapter 13Class 12 notes

What changed from 2025 to 2026

Same 13 NCERT chapters; 2026 replaces the old CBSE one-liners with the full rationalised NCERT sub-heading list and drops the few items NCERT itself removed.

Added or newly named

Miller's experiment
Human Genome Project goals and applications; DNA fingerprinting polymorphism and VNTR; Hershey-Chase; Meselson-Stahl; RNA world
ICSI and IUI (ART)
Pedigree analysis, phenylketonuria, sickle-cell anaemia, aneuploidy/polyploidy, mutation
RNA interference; molecular diagnosis; competent host, PCR, bioreactors, downstream processing
Life history variation; exponential and logistic growth; commensalism and amensalism
Approaches to conservation (narrowly/broadly utilitarian, ethical); cryopreservation, wildlife safaris
Evolution of plants and vertebrates through geological periods

Removed or no longer named

Dengue and chikungunya (Human Health and Disease)
Stem cell technology; vaccine production; biosafety issues
Rice genome project (only Human Genome Project now)
Molecular evidences for evolution; modern synthetic theory; types of natural selection
Red Data Book, Ramsar sites, endangered organisms, extinction, biosphere reserves, national parks (Biodiversity)
Antibiotics 'judicious use'
Significance of seed dispersal

Renumbered

Units I-V (2025) became Units VI-X (2026); 'Chapter-n' labels dropped.

Compared against NTA’s CUET UG 2025 syllabus PDF. When the 2027 syllabus is out, this section will compare 2027 with 2026.

Books to study from

NCERT Biology class 12 (all 13 chapters)

NCERT books are on ncert.nic.in; NIOS course material is on nios.ac.in.

Practise CUET Biology chapter by chapter

The Study OS CUET track follows the chapter map above. Choose Biology as one of your papers, revise a chapter, then test it with exam-style questions and read the explanation after every answer.

Practise CUET Biology

Frequently asked questions

What is the exam pattern of the CUET Biology paper?

CUET UG Biology (paper code 304) has 50 compulsory multiple-choice questions to be answered in 60 minutes. A correct answer earns 5 marks and a wrong answer costs 1 mark, so the paper is out of 250. This is the CUET UG 2026 pattern; NTA has not announced any change for 2027.

Has NTA released the CUET Biology syllabus for 2027?

Not yet. The syllabus on this page is the official CUET UG 2026 Biology syllabus, which is the latest one NTA has published. This page will be updated when the 2027 syllabus is released.

Which books should I study for CUET Biology?

Study from: NCERT Biology class 12 (all 13 chapters).

What changed in the CUET Biology syllabus?

Same 13 NCERT chapters. 2026 replaced the old one-line units with the full NCERT sub-heading list and dropped items NCERT itself removed, such as Red Data Book and dengue. This compares the 2025 and 2026 syllabi; the 2027 syllabus is not out yet.

Is CUET Biology the same as NEET Biology?

CUET Biology is class 12 only: the 13 chapters of NCERT Biology class 12. NEET Biology also covers class 11. If you are preparing for NEET, your class 12 Biology work covers this paper.

Are class 11 Biology chapters in the CUET syllabus?

No. The 2026 CUET Biology syllabus has no class 11 content.